Collections / geo-gse322640

geo-gse322640

Datasets5
Size~293 MB
AssayVisium HD
Samplehuman · bone element
KindComparison
10.1038/s41591-026-04340-7 ↗
Download the whole collection
Python · lamindb 
import lamindb as ln
import spatialdata as sd

coll = ln.Collection.get(key="geo-gse322640")
coll.ordered_artifacts.df()                 # the 5 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]

# …or load each straight into memory as a SpatialData object:
sdatas = {a.key: sd.read_zarr(a.cache()) for a in coll.ordered_artifacts.all()}
About the study

Trabectedin and low-dose irinotecan to target EWS::FLI1 in Ewing sarcoma: a phase 1/2 trial.

Read the abstract at the source →
Member datasets · 5
Open in Vitessce
Visium HD
Human bone element
GSM9555996
human bone element Ewing sarcoma 24 MB 41,222 obs bronze H&E
TechnologyVisium HD
Organismhuman
Tissuebone element
ConditionEwing sarcoma
Size24 MB
Obs41,222
bronze H&E Open in Vitessce
Open in Vitessce
Visium HD
Human bone element
GSM9555997
human bone element Ewing sarcoma 28 MB 26,164 obs bronze H&E
TechnologyVisium HD
Organismhuman
Tissuebone element
ConditionEwing sarcoma
Size28 MB
Obs26,164
bronze H&E Open in Vitessce
Open in Vitessce
Visium HD
Human bone element
GSM9556002
human bone element Ewing sarcoma 144 MB 126,298 obs bronze H&E
TechnologyVisium HD
Organismhuman
Tissuebone element
ConditionEwing sarcoma
Size144 MB
Obs126,298
bronze H&E Open in Vitessce
Open in Vitessce
Visium HD
Human bone element
GSM9556004
human bone element Ewing sarcoma 9.0 MB 13,627 obs silver H&E
TechnologyVisium HD
Organismhuman
Tissuebone element
ConditionEwing sarcoma
Size9.0 MB
Obs13,627
silver H&E Open in Vitessce
Open in Vitessce
Visium HD
Human bone element
GSM9555995
human bone element Ewing sarcoma 88 MB 71,030 obs bronze H&E
TechnologyVisium HD
Organismhuman
Tissuebone element
ConditionEwing sarcoma
Size88 MB
Obs71,030
bronze H&E Open in Vitessce

Cite this collection

doi.org/10.1038/s41591-026-04340-7 ↗
BibTeX 
@article{Grohar_2026,
  title = {Trabectedin and low-dose irinotecan to target EWS::FLI1 in Ewing sarcoma: a phase 1/2 trial},
  volume = {32},
  ISSN = {1546-170X},
  url = {http://dx.doi.org/10.1038/s41591-026-04340-7},
  DOI = {10.1038/s41591-026-04340-7},
  number = {6},
  journal = {Nature Medicine},
  publisher = {Springer Science and Business Media LLC},
  author = {Grohar, Patrick J. and Heise, Rachel and Wedekind, Mary Frances and Ballman, Karla and Mascarenhas, Leo and DuBois, Steven G. and Maki, Robert G. and Boguslawski, Elissa A. and Gedminas, Jenna M. and Wilson, Elizabeth R. and Thomas, Elaine and Segers, Blair and Surrey, Lea F. and Ricker, Cora and Klega, Kelly and Navid, Fariba and Lam, Gretchen Y. and The, Stephanie and Kaufman, Rebecca and Roberts, Ryan D. and Hayashi, Masanori and Mena, Esther and Overman, Lindsey and Peer, Cody and Schmidt, Keith and Diamond, Mark S. and Figg, William D. and Bagatell, Rochelle and Liza Lindenberg, M. and Choyke, Peter L. and Crompton, Brian D. and Widemann, Brigitte C. and Glod, John W. and Laetsch, Theodore W. and Reinke, Denise K. and Chugh, Rashmi},
  year = {2026},
  month = Apr,
  pages = {2227–2237}
}