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Visium

Mouse skin of body

NCBI689

silver Interactive viewer H&E cutaneous melanoma ✓ Verified publication
Mouse skin of body preview
print(sdata)
SpatialData object
├── Images
│     └── 'NCBI689_full_image': DataTree[cyx] (3, 9727, 9792), (3, 4863, 4896), (3, 2431, 2448), (3, 1215, 1224)
├── Shapes
│     └── 'NCBI689_spots': GeoDataFrame shape: (4992, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4992, 31053)
with coordinate systems:
    ▸ 'global', with elements:
        NCBI689_full_image (Images), NCBI689_spots (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("dlaXeYogd61KWnTq")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/dlaXeYogd61KWnTq

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid dlaXeYogd61KWnTq
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["dlaXeYogd61KWnTq0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
Visium
Organism
mouse
Tissue
skin of body
Condition
cutaneous melanoma
Modality
RNA
Observations
4,992
Tier
silver
Chemistry
Visium v1
Resolution
9,792 × 9,727 px
mpp
0.948 µm/px
Size
229 MB
Sample ID
NCBI689
License
CC BY-NC-SA 4.0 NonCommercial
Published
Jul 12, 2022

Cite this dataset

doi.org/10.1038/s41586-022-05242-7 ↗
BibTeX
@article{Karras_2022,
  title = {A cellular hierarchy in melanoma uncouples growth and metastasis},
  volume = {610},
  ISSN = {1476-4687},
  url = {http://dx.doi.org/10.1038/s41586-022-05242-7},
  DOI = {10.1038/s41586-022-05242-7},
  number = {7930},
  journal = {Nature},
  publisher = {Springer Science and Business Media LLC},
  author = {Karras, Panagiotis and Bordeu, Ignacio and Pozniak, Joanna and Nowosad, Ada and Pazzi, Cecilia and Van Raemdonck, Nina and Landeloos, Ewout and Van Herck, Yannick and Pedri, Dennis and Bervoets, Greet and Makhzami, Samira and Khoo, Jia Hui and Pavie, Benjamin and Lamote, Jochen and Marin-Bejar, Oskar and Dewaele, Michael and Liang, Han and Zhang, Xingju and Hua, Yichao and Wouters, Jasper and Browaeys, Robin and Bergers, Gabriele and Saeys, Yvan and Bosisio, Francesca and van den Oord, Joost and Lambrechts, Diether and Rustgi, Anil K. and Bechter, Oliver and Blanpain, Cedric and Simons, Benjamin D. and Rambow, Florian and Marine, Jean-Christophe},
  year = {2022},
  month = Sept,
  pages = {190–198}
}

Source: nature.com ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB