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Visium

Human liver

GSM8155169

bronze Interactive viewer H&E hepatoblastoma Provisional
Human liver preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM8155169_H286_hires_image': DataArray[cyx] (3, 2000, 1957)
│     └── 'GSM8155169_H286_lowres_image': DataArray[cyx] (3, 600, 587)
├── Shapes
│     └── 'GSM8155169_H286': GeoDataFrame shape: (4046, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4046, 17943)
with coordinate systems:
    ▸ 'GSM8155169_H286', with elements:
        GSM8155169_H286_hires_image (Images), GSM8155169_H286_lowres_image (Images), GSM8155169_H286 (Shapes)
    ▸ 'GSM8155169_H286_downscaled_hires', with elements:
        GSM8155169_H286_hires_image (Images), GSM8155169_H286 (Shapes)
    ▸ 'GSM8155169_H286_downscaled_lowres', with elements:
        GSM8155169_H286_lowres_image (Images), GSM8155169_H286 (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("ACP72MeQ6Zk0nPIe")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/ACP72MeQ6Zk0nPIe

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid ACP72MeQ6Zk0nPIe
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["ACP72MeQ6Zk0nPIe0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
Visium
Organism
human
Tissue
liver
Condition
hepatoblastoma
Modality
RNA
Observations
4,046
Tier
bronze
Chemistry
Visium v1
Magnification
other
Resolution
1,957 × 2,000 px
mpp
3.393 µm/px
Size
31 MB
Sample ID
GSM8155169
License
unknown
Published
Feb 7, 2025

Cite this dataset

doi.org/10.1016/j.jhep.2025.01.031 ↗
BibTeX
@article{M_nter_2025,
  title = {Multiomic analysis uncovers a continuous spectrum of differentiation and Wnt-MDK-driven immune evasion in hepatoblastoma},
  volume = {83},
  ISSN = {0168-8278},
  url = {http://dx.doi.org/10.1016/j.jhep.2025.01.031},
  DOI = {10.1016/j.jhep.2025.01.031},
  number = {2},
  journal = {Journal of Hepatology},
  publisher = {Elsevier BV},
  author = {Münter, Daniel and de Faria, Flavia W. and Richter, Mathis and Aranda-Pardos, Irene and Hotfilder, Marc and Walter, Carolin and Paga, Enya and Inserte, Clara and Albert, Thomas K. and Roy, Rajanya and Rahman, Shariyah and Riedel, Nicole C. and Müller, Volker and Pascher, Andreas and Wiebe, Karsten and Schmid, Irene and Vokuhl, Christian and Winkler, Beate and Jüttner, Eva and Vieth, Simon and Mücke, Urs and Kluiver, Thomas A. and Peng, Weng Chuan and Rossig, Claudia and Schlué, Jerome and Madadi-Sanjani, Omid and Sandmann, Sarah and Hartmann, Wolfgang and A-Gonzalez, Noelia and Soehnlein, Oliver and Kerl, Kornelius},
  year = {2025},
  month = Aug,
  pages = {367–382}
}

Source: NCBI GEO ↗ · Reprocessed to SpatialData by SpatialData-DB