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Visium

Mouse eye

NCBI433

silver Interactive viewer H&E Sjogren syndrome ✓ Verified publication
Mouse eye preview
print(sdata)
SpatialData object
├── Images
│     └── 'NCBI433_full_image': DataTree[cyx] (3, 10960, 10606), (3, 5480, 5303), (3, 2740, 2651), (3, 1370, 1325)
├── Shapes
│     └── 'NCBI433_spots': GeoDataFrame shape: (1505, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1505, 32285)
with coordinate systems:
    ▸ 'global', with elements:
        NCBI433_full_image (Images), NCBI433_spots (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("bClRrn9MozQPSTfI")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/bClRrn9MozQPSTfI

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid bClRrn9MozQPSTfI
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["bClRrn9MozQPSTfI0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
Visium
Organism
mouse
Tissue
eye
Condition
Sjogren syndrome
Modality
RNA
Observations
1,505
Tier
silver
Chemistry
Visium v1
Resolution
10,606 × 10,960 px
mpp
0.752 µm/px
Size
221 MB
Sample ID
NCBI433
License
CC BY-NC-SA 4.0 NonCommercial
Published
Sep 23, 2022

Cite this dataset

doi.org/10.3389/fimmu.2022.1011125 ↗
BibTeX
@article{Mauduit_2022,
  title = {Spatial transcriptomics of the lacrimal gland features macrophage activity and epithelium metabolism as key alterations during chronic inflammation},
  volume = {13},
  ISSN = {1664-3224},
  url = {http://dx.doi.org/10.3389/fimmu.2022.1011125},
  DOI = {10.3389/fimmu.2022.1011125},
  journal = {Frontiers in Immunology},
  publisher = {Frontiers Media SA},
  author = {Mauduit, Olivier and Delcroix, Vanessa and Umazume, Takeshi and de Paiva, Cintia S. and Dartt, Darlene A. and Makarenkova, Helen P.},
  year = {2022},
  month = Oct
}

Source: NCBI GEO ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB