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spatial transcriptomics

Human breast

SPA1

bronze Interactive viewer H&E invasive ductal breast carcinoma Provisional
Human breast preview
print(sdata)
SpatialData object
├── Images
│     └── 'SPA1_full_image': DataTree[cyx] (3, 9931, 9277), (3, 4965, 4638), (3, 2482, 2319), (3, 1241, 1159)
├── Shapes
│     └── 'SPA1_spots': GeoDataFrame shape: (264, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (264, 14616)
with coordinate systems:
    ▸ 'global', with elements:
        SPA1_full_image (Images), SPA1_spots (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("sJ28VA6yFx5gcGZg")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/sJ28VA6yFx5gcGZg

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid sJ28VA6yFx5gcGZg
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["sJ28VA6yFx5gcGZg0002"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
spatial transcriptomics
Organism
human
Tissue
breast
Condition
invasive ductal breast carcinoma
Modality
RNA
Observations
264
Tier
bronze
Chemistry
ST 1k
Resolution
9,277 × 9,931 px
mpp
0.685 µm/px
Size
104 MB
Sample ID
SPA1
License
CC BY-NC-SA 4.0 NonCommercial
Published
Jul 1, 2016

Cite this dataset

BibTeX
@article{Ståhl_2016,
  title = {Visualization and analysis of gene expression in tissue sections by spatial transcriptomics},
  author = {Ståhl, PL and Salmén, F and Vickovic, S and Lundmark, A and Navarro, JF and Magnusson, J and Giacomello, S and Asp, M and Westholm, JO and Huss, M and Mollbrink, A and Linnarsson, S and Codeluppi, S and Borg, Å and Pontén, F and Costea, PI and Sahlén, P and Mulder, J and Bergmann, O and Lundeberg, J and Frisén, J},
  journal = {Science (New York, N.Y.)},
  year = {2016},
  volume = {353},
  number = {6294},
  pages = {78-82},
  pmid = {27365449}
}

Source: NCBI GEO ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB