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10x Xenium

Human bone marrow

human-bone-and-bone-marrow-data-with-custom-add-on-panel-1-standard__hbonemarrow-acute-lymphoid-leukemia-section

silver Interactive viewer H&E acute lymphoblastic leukemia No linked publication
Human bone marrow preview
print(sdata)
SpatialData object
├── Images
│     ├── 'he_image': DataTree[cyx] (3, 37252, 11024), (3, 18626, 5512), (3, 9313, 2756), (3, 4656, 1378), (3, 2328, 689)
│     ├── 'morphology_focus': DataTree[cyx] (1, 17145, 48266), (1, 8572, 24133), (1, 4286, 12066), (1, 2143, 6033), (1, 1071, 3016)
│     └── 'morphology_mip': DataTree[cyx] (1, 17145, 48266), (1, 8572, 24133), (1, 4286, 12066), (1, 2143, 6033), (1, 1071, 3016)
├── Labels
│     ├── 'cell_labels': DataTree[yx] (17145, 48266), (8572, 24133), (4286, 12066), (2143, 6033), (1071, 3016)
│     └── 'nucleus_labels': DataTree[yx] (17145, 48266), (8572, 24133), (4286, 12066), (2143, 6033), (1071, 3016)
├── Points
│     └── 'transcripts': DataFrame with shape: (8311608, 10) (3D points)
├── Shapes
│     ├── 'cell_boundaries': GeoDataFrame shape: (225906, 1) (2D shapes)
│     ├── 'cell_circles': GeoDataFrame shape: (225906, 2) (2D shapes)
│     └── 'nucleus_boundaries': GeoDataFrame shape: (225906, 1) (2D shapes)
└── Tables
      └── 'table': AnnData (225906, 477)
with coordinate systems:
    ▸ 'global', with elements:
        he_image (Images), morphology_focus (Images), morphology_mip (Images), cell_labels (Labels), nucleus_labels (Labels), transcripts (Points), cell_boundaries (Shapes), cell_circles (Shapes), nucleus_boundaries (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("aISiYhEynUVzlDd1")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/aISiYhEynUVzlDd1

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid aISiYhEynUVzlDd1
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["aISiYhEynUVzlDd10001"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

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Metadata

Technology
10x Xenium
Organism
human
Tissue
bone marrow
Condition
acute lymphoblastic leukemia
Modality
RNA
Observations
225,906
Transcripts
8,311,608
Tier
silver
Chemistry
Xenium v1
Magnification
40x
Resolution
11,024 × 37,252 px
mpp
0.002 µm/px
Size
2.9 GB
Sample ID
human-bone-and-bone-marrow-data-with-custom-add-on-panel-1-standard__hbonemarrow-acute-lymphoid-leukemia-section
License
CC BY 4.0
Published
Apr 3, 2024

Cite this dataset

No linked publication found — please cite the data source: 10x Genomics ↗.

Source: 10x Genomics ↗ · License: CC BY 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB