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Visium

Human skin of body

MEND40

silver Interactive viewer H&E skin squamous cell carcinoma ✓ Verified publication
Human skin of body preview
print(sdata)
SpatialData object
├── Images
│     └── 'MEND40_full_image': DataTree[cyx] (3, 47104, 48640), (3, 23552, 24320), (3, 11776, 12160), (3, 5888, 6080)
├── Shapes
│     └── 'MEND40_spots': GeoDataFrame shape: (2793, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2793, 33538)
with coordinate systems:
    ▸ 'global', with elements:
        MEND40_full_image (Images), MEND40_spots (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("lYMZtFpcJbilQiqS")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/lYMZtFpcJbilQiqS

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid lYMZtFpcJbilQiqS
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["lYMZtFpcJbilQiqS0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
Visium
Organism
human
Tissue
skin of body
Condition
skin squamous cell carcinoma
Modality
RNA
Observations
2,793
Tier
silver
Chemistry
Visium v1
Magnification
40x
Resolution
48,640 × 47,104 px
mpp
0.172 µm/px
Size
3.1 GB
Sample ID
MEND40
License
CC BY-NC-SA 4.0 NonCommercial
Published
Aug 20, 2021

Cite this dataset

doi.org/10.1016/j.cell.2020.05.039 ↗
BibTeX
@article{Ji_2020,
  title = {Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma},
  volume = {182},
  ISSN = {0092-8674},
  url = {http://dx.doi.org/10.1016/j.cell.2020.05.039},
  DOI = {10.1016/j.cell.2020.05.039},
  number = {2},
  journal = {Cell},
  publisher = {Elsevier BV},
  author = {Ji, Andrew L. and Rubin, Adam J. and Thrane, Kim and Jiang, Sizun and Reynolds, David L. and Meyers, Robin M. and Guo, Margaret G. and George, Benson M. and Mollbrink, Annelie and Bergenstråhle, Joseph and Larsson, Ludvig and Bai, Yunhao and Zhu, Bokai and Bhaduri, Aparna and Meyers, Jordan M. and Rovira-Clavé, Xavier and Hollmig, S. Tyler and Aasi, Sumaira Z. and Nolan, Garry P. and Lundeberg, Joakim and Khavari, Paul A.},
  year = {2020},
  month = July,
  pages = {497–514.e22}
}

Source: NCBI GEO ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB