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Visium

Human placenta

NCBI573

silver Interactive viewer H&E COVID-19 Provisional
Human placenta preview
print(sdata)
SpatialData object
├── Images
│     └── 'NCBI573_full_image': DataTree[cyx] (3, 9324, 9438), (3, 4662, 4719), (3, 2331, 2359), (3, 1165, 1179)
├── Shapes
│     └── 'NCBI573_spots': GeoDataFrame shape: (1547, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (1547, 36601)
with coordinate systems:
    ▸ 'global', with elements:
        NCBI573_full_image (Images), NCBI573_spots (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("y2wB0O2mdW4iPAWO")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/y2wB0O2mdW4iPAWO

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid y2wB0O2mdW4iPAWO
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["y2wB0O2mdW4iPAWO0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
Visium
Organism
human
Tissue
placenta
Condition
COVID-19
Modality
RNA
Observations
1,547
Tier
silver
Chemistry
Visium v1
Resolution
9,438 × 9,324 px
mpp
0.911 µm/px
Size
139 MB
Sample ID
NCBI573
License
CC BY-NC-SA 4.0 NonCommercial
Published
Jul 5, 2023

Cite this dataset

doi.org/10.1016/j.medj.2023.06.003 ↗
BibTeX
@article{Barrozo_2023,
  title = {SARS-CoV-2 niches in human placenta revealed by spatial transcriptomics},
  volume = {4},
  ISSN = {2666-6340},
  url = {http://dx.doi.org/10.1016/j.medj.2023.06.003},
  DOI = {10.1016/j.medj.2023.06.003},
  number = {9},
  journal = {Med},
  publisher = {Elsevier BV},
  author = {Barrozo, Enrico R. and Seferovic, Maxim D. and Castro, Eumenia C.C. and Major, Angela M. and Moorshead, David N. and Jochum, Michael D. and Rojas, Ricardo Ferral and Shope, Cynthia D. and Aagaard, Kjersti M.},
  year = {2023},
  month = Sept,
  pages = {612–634.e4}
}

Source: NCBI GEO ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB