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Visium

Human lung

MISC23

silver Interactive viewer H&E ✓ Verified publication
Human lung preview
print(sdata)
SpatialData object
├── Images
│     └── 'MISC23_full_image': DataTree[cyx] (3, 18432, 32832), (3, 9216, 16416), (3, 4608, 8208), (3, 2304, 4104)
├── Shapes
│     └── 'MISC23_spots': GeoDataFrame shape: (436, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (436, 33538)
with coordinate systems:
    ▸ 'global', with elements:
        MISC23_full_image (Images), MISC23_spots (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("t4gPfhPPrpB5YtJx")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/t4gPfhPPrpB5YtJx

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid t4gPfhPPrpB5YtJx
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["t4gPfhPPrpB5YtJx0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
Visium
Organism
human
Tissue
lung
Modality
RNA
Observations
436
Tier
silver
Chemistry
Visium v1
Magnification
20x
Resolution
32,832 × 18,432 px
mpp
0.456 µm/px
Size
149 MB
Sample ID
MISC23
License
CC BY-NC-SA 4.0 NonCommercial
Published
Dec 21, 2022

Cite this dataset

doi.org/10.1038/s41588-022-01243-4 ↗
BibTeX
@article{Madissoon_2022,
  title = {A spatially resolved atlas of the human lung characterizes a gland-associated immune niche},
  volume = {55},
  ISSN = {1546-1718},
  url = {http://dx.doi.org/10.1038/s41588-022-01243-4},
  DOI = {10.1038/s41588-022-01243-4},
  number = {1},
  journal = {Nature Genetics},
  publisher = {Springer Science and Business Media LLC},
  author = {Madissoon, Elo and Oliver, Amanda J. and Kleshchevnikov, Vitalii and Wilbrey-Clark, Anna and Polanski, Krzysztof and Richoz, Nathan and Ribeiro Orsi, Ana and Mamanova, Lira and Bolt, Liam and Elmentaite, Rasa and Pett, J. Patrick and Huang, Ni and Xu, Chuan and He, Peng and Dabrowska, Monika and Pritchard, Sophie and Tuck, Liz and Prigmore, Elena and Perera, Shani and Knights, Andrew and Oszlanczi, Agnes and Hunter, Adam and Vieira, Sara F. and Patel, Minal and Lindeboom, Rik G. H. and Campos, Lia S. and Matsuo, Kazuhiko and Nakayama, Takashi and Yoshida, Masahiro and Worlock, Kaylee B. and Nikolić, Marko Z. and Georgakopoulos, Nikitas and Mahbubani, Krishnaa T. and Saeb-Parsy, Kourosh and Bayraktar, Omer Ali and Clatworthy, Menna R. and Stegle, Oliver and Kumasaka, Natsuhiko and Teichmann, Sarah A. and Meyer, Kerstin B.},
  year = {2022},
  month = Dec,
  pages = {66–77}
}

Source: nature.com ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB