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Visium

Human kidney

INT2

silver Interactive viewer H&E clear cell renal carcinoma Provisional
Human kidney preview
print(sdata)
SpatialData object
├── Images
│     └── 'INT2_full_image': DataTree[cyx] (3, 19200, 19200), (3, 9600, 9600), (3, 4800, 4800), (3, 2400, 2400)
├── Shapes
│     └── 'INT2_spots': GeoDataFrame shape: (2580, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2580, 36601)
with coordinate systems:
    ▸ 'global', with elements:
        INT2_full_image (Images), INT2_spots (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("Mr1Ymh1MU9n1dcuS")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/Mr1Ymh1MU9n1dcuS

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid Mr1Ymh1MU9n1dcuS
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["Mr1Ymh1MU9n1dcuS0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
Visium
Organism
human
Tissue
kidney
Condition
clear cell renal carcinoma
Modality
RNA
Observations
2,580
Tier
silver
Chemistry
Visium v1
Magnification
20x
Resolution
19,200 × 19,200 px
mpp
0.457 µm/px
Size
563 MB
Sample ID
INT2
License
CC BY-NC-SA 4.0 NonCommercial
Published
Mar 3, 2022

Cite this dataset

doi.org/10.1016/j.immuni.2022.02.001 ↗
BibTeX
@article{Meylan_2022,
  title = {Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer},
  volume = {55},
  ISSN = {1074-7613},
  url = {http://dx.doi.org/10.1016/j.immuni.2022.02.001},
  DOI = {10.1016/j.immuni.2022.02.001},
  number = {3},
  journal = {Immunity},
  publisher = {Elsevier BV},
  author = {Meylan, Maxime and Petitprez, Florent and Becht, Etienne and Bougoüin, Antoine and Pupier, Guilhem and Calvez, Anne and Giglioli, Ilenia and Verkarre, Virginie and Lacroix, Guillaume and Verneau, Johanna and Sun, Chen-Ming and Laurent-Puig, Pierre and Vano, Yann-Alexandre and Elaïdi, Reza and Méjean, Arnaud and Sanchez-Salas, Rafaël and Barret, Eric and Cathelineau, Xavier and Oudard, Stephane and Reynaud, Claude-Agnès and de Reyniès, Aurélien and Sautès-Fridman, Catherine and Fridman, Wolf Herman},
  year = {2022},
  month = Mar,
  pages = {527–541.e5}
}

Source: NCBI GEO ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB