← All datasets
Visium

Human colon

visium-cytassist-human-colon-normal-p5

silver Interactive viewer H&E ✓ Verified publication
Human colon preview
print(sdata)
SpatialData object
├── Images
│     ├── 'Visium_V2_Human_Colon_Normal_P5_full_image': DataTree[cyx] (3, 3000, 3000), (3, 1500, 1500), (3, 750, 750), (3, 375, 375), (3, 187, 187)
│     ├── 'Visium_V2_Human_Colon_Normal_P5_hires_image': DataArray[cyx] (3, 2393, 4000)
│     └── 'Visium_V2_Human_Colon_Normal_P5_lowres_image': DataArray[cyx] (3, 359, 600)
├── Shapes
│     └── 'Visium_V2_Human_Colon_Normal_P5': GeoDataFrame shape: (2638, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2638, 18085)
with coordinate systems:
    ▸ 'Visium_V2_Human_Colon_Normal_P5', with elements:
        Visium_V2_Human_Colon_Normal_P5_full_image (Images), Visium_V2_Human_Colon_Normal_P5_hires_image (Images), Visium_V2_Human_Colon_Normal_P5_lowres_image (Images), Visium_V2_Human_Colon_Normal_P5 (Shapes)
    ▸ 'Visium_V2_Human_Colon_Normal_P5_downscaled_hires', with elements:
        Visium_V2_Human_Colon_Normal_P5_hires_image (Images), Visium_V2_Human_Colon_Normal_P5 (Shapes)
    ▸ 'Visium_V2_Human_Colon_Normal_P5_downscaled_lowres', with elements:
        Visium_V2_Human_Colon_Normal_P5_lowres_image (Images), Visium_V2_Human_Colon_Normal_P5 (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("K3y4WdsggesEJx9t")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/K3y4WdsggesEJx9t

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid K3y4WdsggesEJx9t
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["K3y4WdsggesEJx9t0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue
Part of collection
oliveira-2024-colorectal→
11 datasets · publication

Metadata

Technology
Visium
Organism
human
Tissue
colon
Modality
RNA
Observations
2,638
Tier
silver
Chemistry
Visium CytAssist v2
Resolution
4,000 × 2,393 px
mpp
5.951 µm/px
Size
69 MB
Sample ID
visium-cytassist-human-colon-normal-p5
License
CC BY 4.0
Published
May 15, 2023

Cite this dataset

doi.org/10.1038/s41588-025-02193-3 ↗
BibTeX
@article{Oliveira_2025,
  title = {High-definition spatial transcriptomic profiling of immune cell populations in colorectal cancer},
  volume = {57},
  ISSN = {1546-1718},
  url = {http://dx.doi.org/10.1038/s41588-025-02193-3},
  DOI = {10.1038/s41588-025-02193-3},
  number = {6},
  journal = {Nature Genetics},
  publisher = {Springer Science and Business Media LLC},
  author = {Oliveira, Michelli Faria de and Romero, Juan Pablo and Chung, Meii and Williams, Stephen R. and Gottscho, Andrew D. and Gupta, Anushka and Pilipauskas, Susan E. and Mohabbat, Seayar and Raman, Nandhini and Sukovich, David J. and Patterson, David M. and de Oliveira, Michelli Faria and Romero, Juan Pablo and Williams, Stephen R. and Patterson, David M. and Taylor, Sarah E. B. and Taylor, Sarah E. B.},
  year = {2025},
  month = June,
  pages = {1512–1523}
}

Source: 10x Genomics ↗ · License: CC BY 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB