← All datasets
Visium

Human colon

GSM6505133

silver Interactive viewer H&E adenocarcinoma ✓ Verified publication
Human colon preview
print(sdata)
SpatialData object
├── Images
│     ├── 'GSM6505133_DonorA_FFPE-probes_full_image': DataTree[cyx] (3, 37256, 38716), (3, 18628, 19358), (3, 9314, 9679), (3, 4657, 4839), (3, 2328, 2419)
│     └── 'GSM6505133_DonorA_FFPE-probes_hires_image': DataArray[cyx] (3, 1925, 2000)
├── Shapes
│     └── 'GSM6505133_DonorA_FFPE-probes': GeoDataFrame shape: (2204, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (2204, 18035)
with coordinate systems:
    ▸ 'GSM6505133_DonorA_FFPE-probes', with elements:
        GSM6505133_DonorA_FFPE-probes_full_image (Images), GSM6505133_DonorA_FFPE-probes_hires_image (Images), GSM6505133_DonorA_FFPE-probes (Shapes)
    ▸ 'GSM6505133_DonorA_FFPE-probes_downscaled_hires', with elements:
        GSM6505133_DonorA_FFPE-probes_hires_image (Images), GSM6505133_DonorA_FFPE-probes (Shapes)
    ▸ 'GSM6505133_DonorA_FFPE-probes_downscaled_lowres', with elements:
        GSM6505133_DonorA_FFPE-probes (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("fsVBVE8Vt4tYAbnL")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/fsVBVE8Vt4tYAbnL

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid fsVBVE8Vt4tYAbnL
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["fsVBVE8Vt4tYAbnL0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue
Part of collection
Assessment of Spatial Genomics for Oncology Discovery→
29 datasets · other

Metadata

Technology
Visium
Organism
human
Tissue
colon
Condition
adenocarcinoma
Modality
RNA
Observations
2,204
Tier
silver
Chemistry
Visium v1
Magnification
40x
Resolution
38,716 × 37,256 px
mpp
0.186 µm/px
Size
1.5 GB
Sample ID
GSM6505133
License
unknown
Published
Nov 1, 2022

Cite this dataset

doi.org/10.1016/j.crmeth.2022.100340 ↗
BibTeX
@article{Lyubetskaya_2022,
  title = {Assessment of spatial transcriptomics for oncology discovery},
  volume = {2},
  ISSN = {2667-2375},
  url = {http://dx.doi.org/10.1016/j.crmeth.2022.100340},
  DOI = {10.1016/j.crmeth.2022.100340},
  number = {11},
  journal = {Cell Reports Methods},
  publisher = {Elsevier BV},
  author = {Lyubetskaya, Anna and Rabe, Brian and Fisher, Andrew and Lewin, Anne and Neuhaus, Isaac and Brett, Constance and Brett, Todd and Pereira, Ethel and Golhar, Ryan and Kebede, Sami and Font-Tello, Alba and Mosure, Kathy and Van Wittenberghe, Nicholas and Mavrakis, Konstantinos J. and MacIsaac, Kenzie and Chen, Benjamin J. and Drokhlyansky, Eugene},
  year = {2022},
  month = Nov,
  pages = {100340}
}

Source: NCBI GEO ↗ · Reprocessed to SpatialData by SpatialData-DB