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Visium

Human brain

MISC10

silver Interactive viewer H&E ✓ Verified publication
Human brain preview
print(sdata)
SpatialData object
├── Images
│     └── 'MISC10_full_image': DataTree[cyx] (3, 13332, 13332), (3, 6666, 6666), (3, 3333, 3333), (3, 1666, 1666)
├── Shapes
│     └── 'MISC10_spots': GeoDataFrame shape: (4789, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4789, 33538)
with coordinate systems:
    ▸ 'global', with elements:
        MISC10_full_image (Images), MISC10_spots (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("snUq58ryiwR14aDn")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/snUq58ryiwR14aDn

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid snUq58ryiwR14aDn
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["snUq58ryiwR14aDn0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
Visium
Organism
human
Tissue
brain
Modality
RNA
Observations
4,789
Tier
silver
Chemistry
Visium v1
Resolution
13,332 × 13,332 px
mpp
0.726 µm/px
Size
509 MB
Sample ID
MISC10
License
CC BY-NC-SA 4.0 NonCommercial
Published
Feb 8, 2021

Cite this dataset

doi.org/10.1038/s41593-020-00787-0 ↗
BibTeX
@article{Maynard_2021,
  title = {Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex},
  volume = {24},
  ISSN = {1546-1726},
  url = {http://dx.doi.org/10.1038/s41593-020-00787-0},
  DOI = {10.1038/s41593-020-00787-0},
  number = {3},
  journal = {Nature Neuroscience},
  publisher = {Springer Science and Business Media LLC},
  author = {Maynard, Kristen R. and Collado-Torres, Leonardo and Weber, Lukas M. and Uytingco, Cedric and Barry, Brianna K. and Williams, Stephen R. and Catallini, Joseph L. and Tran, Matthew N. and Besich, Zachary and Tippani, Madhavi and Chew, Jennifer and Yin, Yifeng and Kleinman, Joel E. and Hyde, Thomas M. and Rao, Nikhil and Hicks, Stephanie C. and Martinowich, Keri and Jaffe, Andrew E.},
  year = {2021},
  month = Feb,
  pages = {425–436}
}

Source: nature.com ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB