← All datasets
Visium

Human brain

NCBI655

silver Interactive viewer H&E Parkinson disease ✓ Verified publication
Human brain preview
print(sdata)
SpatialData object
├── Images
│     └── 'NCBI655_full_image': DataTree[cyx] (3, 47104, 48640), (3, 23552, 24320), (3, 11776, 12160), (3, 5888, 6080)
├── Shapes
│     └── 'NCBI655_spots': GeoDataFrame shape: (4984, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (4984, 17943)
with coordinate systems:
    ▸ 'global', with elements:
        NCBI655_full_image (Images), NCBI655_spots (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("mueTboGZxsjmbkLA")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/mueTboGZxsjmbkLA

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid mueTboGZxsjmbkLA
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["mueTboGZxsjmbkLA0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

View on Lamin ↗ Open in Vitessce ↗ Flag a data issue

Metadata

Technology
Visium
Organism
human
Tissue
brain
Condition
Parkinson disease
Modality
RNA
Observations
4,984
Tier
silver
Chemistry
Visium v1
Magnification
40x
Resolution
48,640 × 47,104 px
mpp
0.172 µm/px
Size
4.9 GB
Sample ID
NCBI655
License
CC BY-NC-SA 4.0 NonCommercial
Published
May 21, 2023

Cite this dataset

doi.org/10.1038/s41587-023-01937-y ↗
BibTeX
@article{Vicari_2023,
  title = {Spatial multimodal analysis of transcriptomes and metabolomes in tissues},
  volume = {42},
  ISSN = {1546-1696},
  url = {http://dx.doi.org/10.1038/s41587-023-01937-y},
  DOI = {10.1038/s41587-023-01937-y},
  number = {7},
  journal = {Nature Biotechnology},
  publisher = {Springer Science and Business Media LLC},
  author = {Vicari, Marco and Mirzazadeh, Reza and Nilsson, Anna and Shariatgorji, Reza and Bjärterot, Patrik and Larsson, Ludvig and Lee, Hower and Nilsson, Mats and Foyer, Julia and Ekvall, Markus and Czarnewski, Paulo and Zhang, Xiaoqun and Svenningsson, Per and Käll, Lukas and Andrén, Per E. and Lundeberg, Joakim},
  year = {2023},
  month = Sept,
  pages = {1046–1050}
}

Source: nature.com ↗ · License: CC BY-NC-SA 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB