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10x Xenium

Mouse forebrain

GSM8965607

silver Interactive viewer ✓ Verified publication
Mouse forebrain preview
print(sdata)
SpatialData object
├── Images
│     ├── 'morphology_focus': DataTree[cyx] (1, 37568, 39896), (1, 18784, 19948), (1, 9392, 9974), (1, 4696, 4987), (1, 2348, 2493)
│     └── 'morphology_mip': DataTree[cyx] (1, 37568, 39896), (1, 18784, 19948), (1, 9392, 9974), (1, 4696, 4987), (1, 2348, 2493)
├── Labels
│     ├── 'cell_labels': DataTree[yx] (37568, 39896), (18784, 19948), (9392, 9974), (4696, 4987), (2348, 2493)
│     └── 'nucleus_labels': DataTree[yx] (37568, 39896), (18784, 19948), (9392, 9974), (4696, 4987), (2348, 2493)
├── Points
│     └── 'transcripts': DataFrame with shape: (60971125, 10) (3D points)
├── Shapes
│     ├── 'cell_boundaries': GeoDataFrame shape: (99608, 1) (2D shapes)
│     ├── 'cell_circles': GeoDataFrame shape: (99608, 2) (2D shapes)
│     └── 'nucleus_boundaries': GeoDataFrame shape: (99608, 1) (2D shapes)
└── Tables
      └── 'table': AnnData (99608, 480)
with coordinate systems:
    ▸ 'global', with elements:
        morphology_focus (Images), morphology_mip (Images), cell_labels (Labels), nucleus_labels (Labels), transcripts (Points), cell_boundaries (Shapes), cell_circles (Shapes), nucleus_boundaries (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("aHKR5QROlCrl8CO2")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/aHKR5QROlCrl8CO2

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid aHKR5QROlCrl8CO2
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["aHKR5QROlCrl8CO20000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
10x Xenium
Organism
mouse
Tissue
forebrain
Modality
RNA
Observations
99,608
Transcripts
60,971,125
Tier
silver
Chemistry
Xenium v1
Size
5.6 GB
Sample ID
GSM8965607
License
NCBI GEO policy
Published
Aug 1, 2025

Cite this dataset

doi.org/10.1523/eneuro.0046-25.2025 ↗
BibTeX
@article{Ebert_2025,
  title = {Single-Cell Approaches Define the Murine Leptomeninges: Cortical Brain Interface as a Distinct Cellular Neighborhood Composed of Neural and Non-neural Cell Types},
  volume = {12},
  ISSN = {2373-2822},
  url = {http://dx.doi.org/10.1523/eneuro.0046-25.2025},
  DOI = {10.1523/eneuro.0046-25.2025},
  number = {8},
  journal = {eneuro},
  publisher = {Society for Neuroscience},
  author = {Ebert, Sarah N. and Eisner, Christine and Karamboulas, Konstantina and Bernier, Louis-Philippe and Kaplan, David R. and MacVicar, Brian A. and Miller, Freda D.},
  year = {2025},
  month = Aug,
  pages = {ENEURO.0046–25.2025}
}

Source: NCBI GEO ↗ · License: NCBI GEO policy ↗ · Reprocessed to SpatialData by SpatialData-DB