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10x Xenium

Human colon

ffpe-human-colorectal-cancer-data-with-human-immuno-oncology-profiling-panel-and-custom-add-on-1-standard

silver Interactive viewer H&E colorectal cancer No linked publication
Human colon preview
print(sdata)
SpatialData object
├── Images
│     ├── 'he_image': DataTree[cyx] (3, 40815, 21507), (3, 20407, 10753), (3, 10203, 5376), (3, 5101, 2688), (3, 2550, 1344)
│     └── 'morphology_focus': DataTree[cyx] (1, 20493, 51115), (1, 10246, 25557), (1, 5123, 12778), (1, 2561, 6389), (1, 1280, 3194)
├── Labels
│     ├── 'cell_labels': DataTree[yx] (20493, 51115), (10246, 25557), (5123, 12778), (2561, 6389), (1280, 3194)
│     └── 'nucleus_labels': DataTree[yx] (20493, 51115), (10246, 25557), (5123, 12778), (2561, 6389), (1280, 3194)
├── Points
│     └── 'transcripts': DataFrame with shape: (49931223, 11) (3D points)
├── Shapes
│     ├── 'cell_boundaries': GeoDataFrame shape: (388175, 1) (2D shapes)
│     ├── 'cell_circles': GeoDataFrame shape: (388175, 2) (2D shapes)
│     └── 'nucleus_boundaries': GeoDataFrame shape: (388175, 2) (2D shapes)
└── Tables
      └── 'table': AnnData (388175, 480)
with coordinate systems:
    ▸ 'global', with elements:
        he_image (Images), morphology_focus (Images), cell_labels (Labels), nucleus_labels (Labels), transcripts (Points), cell_boundaries (Shapes), cell_circles (Shapes), nucleus_boundaries (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("iidMPcbVlfusWRbP")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/iidMPcbVlfusWRbP

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid iidMPcbVlfusWRbP
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["iidMPcbVlfusWRbP0001"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
10x Xenium
Organism
human
Tissue
colon
Condition
colorectal cancer
Modality
RNA
Observations
388,175
Transcripts
49,931,223
Tier
silver
Chemistry
Xenium v1
Magnification
40x
Resolution
21,507 × 40,815 px
mpp
0.001 µm/px
Size
5.4 GB
Sample ID
ffpe-human-colorectal-cancer-data-with-human-immuno-oncology-profiling-panel-and-custom-add-on-1-standard
License
CC BY 4.0
Published
May 14, 2024

Cite this dataset

No linked publication found — please cite the data source: 10x Genomics ↗.

Source: 10x Genomics ↗ · License: CC BY 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB