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10x Xenium

Mouse brain

xenium-in-situ-analysis-of-alzheimers-disease-mouse-model-brain-coronal-sections-from-one-hemisphere-over-a-time-course-1-standard__ffpe-tgcrnd8-5-7-months

silver Interactive viewer Alzheimer disease No linked publication
Mouse brain preview
print(sdata)
SpatialData object
├── Images
│     ├── 'morphology_focus': DataTree[cyx] (1, 20741, 28491), (1, 10370, 14245), (1, 5185, 7122), (1, 2592, 3561), (1, 1296, 1780)
│     └── 'morphology_mip': DataTree[cyx] (1, 20741, 28491), (1, 10370, 14245), (1, 5185, 7122), (1, 2592, 3561), (1, 1296, 1780)
├── Labels
│     ├── 'cell_labels': DataTree[yx] (20741, 28491), (10370, 14245), (5185, 7122), (2592, 3561), (1296, 1780)
│     └── 'nucleus_labels': DataTree[yx] (20741, 28491), (10370, 14245), (5185, 7122), (2592, 3561), (1296, 1780)
├── Points
│     └── 'transcripts': DataFrame with shape: (14687596, 10) (3D points)
├── Shapes
│     ├── 'cell_boundaries': GeoDataFrame shape: (58682, 1) (2D shapes)
│     ├── 'cell_circles': GeoDataFrame shape: (58682, 2) (2D shapes)
│     └── 'nucleus_boundaries': GeoDataFrame shape: (58682, 1) (2D shapes)
└── Tables
      └── 'table': AnnData (58682, 347)
with coordinate systems:
    ▸ 'global', with elements:
        morphology_focus (Images), morphology_mip (Images), cell_labels (Labels), nucleus_labels (Labels), transcripts (Points), cell_boundaries (Shapes), cell_circles (Shapes), nucleus_boundaries (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("y56H11pO57bvzSpl")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/y56H11pO57bvzSpl

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid y56H11pO57bvzSpl
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["y56H11pO57bvzSpl0000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
10x Xenium
Organism
mouse
Tissue
brain
Condition
Alzheimer disease
Modality
RNA
Observations
58,682
Transcripts
14,687,596
Tier
silver
Chemistry
Xenium v1
Size
1.9 GB
Sample ID
xenium-in-situ-analysis-of-alzheimers-disease-mouse-model-brain-coronal-sections-from-one-hemisphere-over-a-time-course-1-standard__ffpe-tgcrnd8-5-7-months
License
CC BY 4.0
Published
Jul 13, 2023

Cite this dataset

No linked publication found — please cite the data source: 10x Genomics ↗.

Source: 10x Genomics ↗ · License: CC BY 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB