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10x Xenium

Mouse brain

xenium-in-situ-analysis-of-alzheimers-disease-mouse-model-brain-coronal-sections-from-one-hemisphere-over-a-time-course-1-standard__ffpe-tgcrnd8-17-9-months

silver Interactive viewer Alzheimer disease No linked publication
Mouse brain preview
print(sdata)
SpatialData object
├── Images
│     ├── 'morphology_focus': DataTree[cyx] (1, 24864, 31348), (1, 12432, 15674), (1, 6216, 7837), (1, 3108, 3918), (1, 1554, 1959)
│     └── 'morphology_mip': DataTree[cyx] (1, 24864, 31348), (1, 12432, 15674), (1, 6216, 7837), (1, 3108, 3918), (1, 1554, 1959)
├── Labels
│     ├── 'cell_labels': DataTree[yx] (24864, 31348), (12432, 15674), (6216, 7837), (3108, 3918), (1554, 1959)
│     └── 'nucleus_labels': DataTree[yx] (24864, 31348), (12432, 15674), (6216, 7837), (3108, 3918), (1554, 1959)
├── Points
│     └── 'transcripts': DataFrame with shape: (15687982, 10) (3D points)
├── Shapes
│     ├── 'cell_boundaries': GeoDataFrame shape: (62268, 1) (2D shapes)
│     ├── 'cell_circles': GeoDataFrame shape: (62268, 2) (2D shapes)
│     └── 'nucleus_boundaries': GeoDataFrame shape: (62268, 1) (2D shapes)
└── Tables
      └── 'table': AnnData (62268, 347)
with coordinate systems:
    ▸ 'global', with elements:
        morphology_focus (Images), morphology_mip (Images), cell_labels (Labels), nucleus_labels (Labels), transcripts (Points), cell_boundaries (Shapes), cell_circles (Shapes), nucleus_boundaries (Shapes)
Load in Python
import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
artifact = db.Artifact.get("Ba2TpookPefUzPq6")   # latest version

sdata = artifact.load()   # cache, then load into memory
group = artifact.open()   # stream without downloading
path  = artifact.cache()  # sync into the local cache, returns the path
Load from the CLI
# one-shot: cache the dataset and print its local path
lamin load https://lamin.ai/scverse/spatialdata-db/artifact/Ba2TpookPefUzPq6

# or connect once, then load by uid
lamin connect scverse/spatialdata-db
lamin load artifact --uid Ba2TpookPefUzPq6
Load with the Python client
# pip install git+https://github.com/theislab/spatialdata-db-client
from sddb import Catalog

ds = Catalog().cohort(uids=["Ba2TpookPefUzPq60000"])[0]
ds.elements()                 # inspect without downloading
sdata = ds.load(lazy=False)   # copy to the local cache and open

Docs: finding & loading data →

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Metadata

Technology
10x Xenium
Organism
mouse
Tissue
brain
Condition
Alzheimer disease
Modality
RNA
Observations
62,268
Transcripts
15,687,982
Tier
silver
Chemistry
Xenium v1
Size
2.2 GB
Sample ID
xenium-in-situ-analysis-of-alzheimers-disease-mouse-model-brain-coronal-sections-from-one-hemisphere-over-a-time-course-1-standard__ffpe-tgcrnd8-17-9-months
License
CC BY 4.0
Published
Jul 13, 2023

Cite this dataset

No linked publication found — please cite the data source: 10x Genomics ↗.

Source: 10x Genomics ↗ · License: CC BY 4.0 ↗ · Reprocessed to SpatialData by SpatialData-DB