Collections / Immune Dynamics in Palmoplantar Pustulosis Unveiled by Single-Cell and High-Resolution Spatial Transcriptomics [Spatial Transcriptomics]

Immune Dynamics in Palmoplantar Pustulosis Unveiled by Single-Cell and High-Resolution Spatial Transcriptomics [Spatial Transcriptomics]

Immune dynamics in palmoplantar pustulosis (human skin, Visium HD).

Datasets2
Size~457 MB
AssayVisium HD
Samplehuman · skin of body
KindPublication
10.1016/j.jaci.2026.01.028 ↗
Python · lamindb
import lamindb as ln
import spatialdata as sd

coll = ln.Collection.get(key="geo-gse299051-palmoplantar-pustulosis")
coll.ordered_artifacts.df()                 # the 2 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]

# …or load each straight into memory as a SpatialData object:
sdatas = {a.key: sd.read_zarr(a.cache()) for a in coll.ordered_artifacts.all()}

Single-cell and spatial transcriptomics unveil myeloid-lymphoid cross talk and the dermal immune niche underlying palmoplantar pustulosis.

Read the abstract at the source →
Open in Vitessce
Visium HD
Human skin of body
GSM9031941
human skin of body pustulosis palmaris et plantaris 247 MB 100,038 obs silver H&E
TechnologyVisium HD
Organismhuman
Tissueskin of body
Conditionpustulosis palmaris et plantaris
Size247 MB
Obs100,038
silver H&E Open in Vitessce
Open in Vitessce
Visium HD
Human skin of body
GSM9031942
human skin of body pustulosis palmaris et plantaris 210 MB 84,472 obs silver H&E
TechnologyVisium HD
Organismhuman
Tissueskin of body
Conditionpustulosis palmaris et plantaris
Size210 MB
Obs84,472
silver H&E Open in Vitessce

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