Collections / Targeting circulating mechanoresponsive monocytes and macrophages to reduce fibrosis

Targeting circulating mechanoresponsive monocytes and macrophages to reduce fibrosis

We performed single-cell RNA sequencing on skin, wounded tissue, or wounded tissue subjected to mechanical strain. Wounds could be treated with focal adhesion kinase inhibitor (FAKI) hydrogels or in mice with FAK knocked out in the myeloid cells.

Datasets2
Size~20 MB
AssayVisium
Samplehuman · skin of body
KindOther
PMID:41120571 ↗
Python · lamindb
import lamindb as ln
import spatialdata as sd

coll = ln.Collection.get(key="geo-gse297064")
coll.ordered_artifacts.df()                 # the 2 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]

# …or load each straight into memory as a SpatialData object:
sdatas = {a.key: sd.read_zarr(a.cache()) for a in coll.ordered_artifacts.all()}
Visium
Human skin of body
GSM8983043
human skin of body 12 MB 2,581 obs bronze H&E
TechnologyVisium
Organismhuman
Tissueskin of body
Size12 MB
Obs2,581
bronze H&E
Open in Vitessce
Visium
Human skin of body
GSM8983044
human skin of body 7.6 MB 943 obs bronze H&E
TechnologyVisium
Organismhuman
Tissueskin of body
Size7.6 MB
Obs943
bronze H&E Open in Vitessce

Cite this collection

No linked publication found — please cite the data source.