Collections / Hif2α–Lox mediated collagen remodelling is crucial for embryo invasion

Hif2α–Lox mediated collagen remodelling is crucial for embryo invasion

The mouse uterine gene expressions on pregnancy day 6 were investigated by Visium spatial transcriptome. Contributions of Hif2a-Lox axis was examined by comparing uterine-specific KO mice of Hif2a or Lox with their littermate control.

Datasets6
Size~83 MB
AssayVisium
Samplemouse · uterus
KindComparison
PMID:41803091 ↗
Python · lamindb
import lamindb as ln
import spatialdata as sd

coll = ln.Collection.get(key="geo-gse274059")
coll.ordered_artifacts.df()                 # the 6 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]

# …or load each straight into memory as a SpatialData object:
sdatas = {a.key: sd.read_zarr(a.cache()) for a in coll.ordered_artifacts.all()}
Open in Vitessce
Visium
Mouse uterus
GSM8442781
mouse uterus 12 MB 408 obs bronze H&E
TechnologyVisium
Organismmouse
Tissueuterus
Size12 MB
Obs408
Magnificationother · 3.623 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Mouse uterus
GSM8442780
mouse uterus 13 MB 454 obs bronze H&E
TechnologyVisium
Organismmouse
Tissueuterus
Size13 MB
Obs454
Magnificationother · 3.624 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Mouse uterus
GSM8442777
mouse uterus 13 MB 533 obs bronze H&E
TechnologyVisium
Organismmouse
Tissueuterus
Size13 MB
Obs533
Magnificationother · 3.622 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Mouse uterus
GSM8442779
mouse uterus 14 MB 436 obs bronze H&E
TechnologyVisium
Organismmouse
Tissueuterus
Size14 MB
Obs436
Magnificationother · 3.622 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Mouse uterus
GSM8442778
mouse uterus 18 MB 662 obs bronze H&E
TechnologyVisium
Organismmouse
Tissueuterus
Size18 MB
Obs662
Magnificationother · 3.623 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Mouse uterus
GSM8442776
mouse uterus 11 MB 369 obs bronze H&E
TechnologyVisium
Organismmouse
Tissueuterus
Size11 MB
Obs369
bronze H&E Open in Vitessce

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