Collections / The roles of glioma-associated macrophages/microglia in human GBM

The roles of glioma-associated macrophages/microglia in human GBM

The tumor microenvironment of glioblastoma (GBM) is characterized by a high proportion of glioma-associated macrophages/microglia (GAMs). We performed spatial analysis (Visium) to profile GAMs in human GBM.

Datasets4
Size~362 MB
AssayVisium
Samplehuman · brain
KindOther
PMID:39921277 ↗
Python · lamindb
import lamindb as ln
import spatialdata as sd

coll = ln.Collection.get(key="geo-gse273432")
coll.ordered_artifacts.df()                 # the 4 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]

# …or load each straight into memory as a SpatialData object:
sdatas = {a.key: sd.read_zarr(a.cache()) for a in coll.ordered_artifacts.all()}
Open in Vitessce
Visium
Human brain
GSM8428201
human brain glioblastoma 95 MB 4,437 obs bronze H&E
TechnologyVisium
Organismhuman
Tissuebrain
Conditionglioblastoma
Size95 MB
Obs4,437
Magnificationother · 4.916 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Human brain
GSM8428200
human brain glioblastoma 85 MB 3,638 obs bronze H&E
TechnologyVisium
Organismhuman
Tissuebrain
Conditionglioblastoma
Size85 MB
Obs3,638
Magnificationother · 3.753 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Human brain
GSM8428199
human brain glioblastoma 104 MB 4,992 obs bronze H&E
TechnologyVisium
Organismhuman
Tissuebrain
Conditionglioblastoma
Size104 MB
Obs4,992
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Human brain
GSM8428202
human brain glioblastoma 79 MB 4,635 obs bronze H&E
TechnologyVisium
Organismhuman
Tissuebrain
Conditionglioblastoma
Size79 MB
Obs4,635
bronze H&E Open in Vitessce

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