Collections / Specific oncogenic drivers differently shaped the composition and functional diversity of immune cells in the microenvironment of experimental gliomas

Specific oncogenic drivers differently shaped the composition and functional diversity of immune cells in the microenvironment of experimental gliomas

We performed spatial transcriptomics to profile spatial localization and intercations of cell populations within GL261 glioma mouse model. Funding: The Polish National Science Center 2020/39/B/NZ4/02683 (BK).

Datasets3
Size~100 MB
AssayVisium
Samplemouse · brain
KindComparison
www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE269545 ↗
Python · lamindb
import lamindb as ln
import spatialdata as sd

coll = ln.Collection.get(key="geo-gse269545")
coll.ordered_artifacts.df()                 # the 3 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]

# …or load each straight into memory as a SpatialData object:
sdatas = {a.key: sd.read_zarr(a.cache()) for a in coll.ordered_artifacts.all()}
Open in Vitessce
Visium
Mouse brain
GSM8321875
mouse brain glioma 23 MB 2,208 obs silver H&E
TechnologyVisium
Organismmouse
Tissuebrain
Conditionglioma
Size23 MB
Obs2,208
silver H&E Open in Vitessce
Open in Vitessce
Visium
Mouse brain
GSM8321878
mouse brain glioma 42 MB 2,769 obs silver H&E
TechnologyVisium
Organismmouse
Tissuebrain
Conditionglioma
Size42 MB
Obs2,769
silver H&E Open in Vitessce
Open in Vitessce
Visium
Mouse brain
GSM8321877
mouse brain glioma 36 MB 2,327 obs silver H&E
TechnologyVisium
Organismmouse
Tissuebrain
Conditionglioma
Size36 MB
Obs2,327
silver H&E Open in Vitessce

Cite this collection

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