Collections / Spatial transcriptome gene expression profile in 2 patients with Hashimoto's thyroiditis and 2 patients with papillary thyroid cancer combined with Hashimoto's thyroiditis.

Spatial transcriptome gene expression profile in 2 patients with Hashimoto's thyroiditis and 2 patients with papillary thyroid cancer combined with Hashimoto's thyroiditis.

Hashimoto's thyroiditis and papillary thyroid cancer are the most common thyroid disorders. We used spatial transcriptome sequencing (ST-seq) to investigate their potential relationship.

Datasets3
Size~97 MB
AssayVisium
Samplehuman · thyroid gland
KindReplicates
PMID:39178310 ↗
Python · lamindb
import lamindb as ln
import spatialdata as sd

coll = ln.Collection.get(key="geo-gse230424")
coll.ordered_artifacts.df()                 # the 3 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]

# …or load each straight into memory as a SpatialData object:
sdatas = {a.key: sd.read_zarr(a.cache()) for a in coll.ordered_artifacts.all()}
Open in Vitessce
Visium
Human thyroid gland
GSM7221916
human thyroid gland Hashimoto thyroiditis 26 MB 3,154 obs silver H&E
TechnologyVisium
Organismhuman
Tissuethyroid gland
ConditionHashimoto thyroiditis
Size26 MB
Obs3,154
silver H&E Open in Vitessce
Open in Vitessce
Visium
Human thyroid gland
GSM7221918
human thyroid gland Hashimoto thyroiditis 37 MB 4,626 obs silver H&E
TechnologyVisium
Organismhuman
Tissuethyroid gland
ConditionHashimoto thyroiditis
Size37 MB
Obs4,626
silver H&E Open in Vitessce
Open in Vitessce
Visium
Human thyroid gland
GSM7221915
human thyroid gland Hashimoto thyroiditis 34 MB 3,647 obs silver H&E
TechnologyVisium
Organismhuman
Tissuethyroid gland
ConditionHashimoto thyroiditis
Size34 MB
Obs3,647
silver H&E Open in Vitessce

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