Collections / INPP5D limits plaque formation and glial reactivity in the APP/PS1 mouse model of Alzheimer’s disease
INPP5D limits plaque formation and glial reactivity in the APP/PS1 mouse model of Alzheimer’s disease
Spatial Transcriptomics (Visium) of 12 coronal brain sections from 6 months old female Inpp5dfl/fl/Cx3cr1CreER/+ crossed to APPKM670/671NL/PSEN1Δexon9 (PSAPP) mice and treated with either cornoil or tamoxifen (75 mg/kg) at 3 months of age for 5 consecutive days
Datasets12
Size~717 MB
AssayVisium
Samplemouse · brain
KindComparison
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Python · lamindb
import lamindb as ln
import spatialdata as sd
coll = ln.Collection.get(key="geo-gse203424")
coll.ordered_artifacts.df() # the 12 members, ordered
# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]
# …or load each straight into memory as a SpatialData object:
sdatas = {a.key: sd.read_zarr(a.cache()) for a in coll.ordered_artifacts.all()} Member datasets · 12
Mouse brain
GSM6171793
mouse brain Alzheimer disease 52 MB 2,775 obs bronze H&E
TechnologyVisium
Organismmouse
Tissuebrain
ConditionAlzheimer disease
Obs2,775
bronze H&E
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