Collections / A novel model of binge ethanol exposure reveals enhanced neurodegeneration with advanced age

A novel model of binge ethanol exposure reveals enhanced neurodegeneration with advanced age

Datasets4
Size~3.3 GB
AssayVisium
Samplemouse · brain
KindComparison
10.1016/j.bbi.2023.12.034 ↗
Download the whole collection
Python · lamindb 
import lamindb as ln
import spatialdata as sd

coll = ln.Collection.get(key="doi-10.1016/j.bbi.2023.12.034")
coll.ordered_artifacts.df()                 # the 4 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]

# …or load each straight into memory as a SpatialData object:
sdatas = {a.key: sd.read_zarr(a.cache()) for a in coll.ordered_artifacts.all()}
About the study

Binge ethanol exposure in advanced age elevates neuroinflammation and early indicators of neurodegeneration and cognitive impairment in female mice.

Read the abstract at the source →
Member datasets · 4
Open in Vitessce
Visium
Mouse brain
NCBI802
mouse brain 855 MB 2,743 obs silver H&E
TechnologyVisium
Organismmouse
Tissuebrain
Size855 MB
Obs2,743
Magnification20x · 0.468 µm/px
silver H&E Open in Vitessce
Open in Vitessce
Visium
Mouse brain
NCBI801
mouse brain 854 MB 2,889 obs bronze H&E
TechnologyVisium
Organismmouse
Tissuebrain
Size854 MB
Obs2,889
Magnification20x · 0.468 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Mouse brain
NCBI799
mouse brain 845 MB 2,648 obs bronze H&E
TechnologyVisium
Organismmouse
Tissuebrain
Size845 MB
Obs2,648
Magnification20x · 0.468 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Mouse brain
NCBI800
mouse brain 856 MB 2,784 obs silver H&E
TechnologyVisium
Organismmouse
Tissuebrain
Size856 MB
Obs2,784
Magnification20x · 0.468 µm/px
silver H&E Open in Vitessce

Cite this collection

doi.org/10.1016/j.bbi.2023.12.034 ↗
BibTeX 
@article{Anton_2024,
  title = {Binge ethanol exposure in advanced age elevates neuroinflammation and early indicators of neurodegeneration and cognitive impairment in female mice},
  volume = {116},
  ISSN = {0889-1591},
  url = {http://dx.doi.org/10.1016/j.bbi.2023.12.034},
  DOI = {10.1016/j.bbi.2023.12.034},
  journal = {Brain, Behavior, and Immunity},
  publisher = {Elsevier BV},
  author = {Anton, Paige E. and Rutt, Lauren N. and Kaufman, Michael L. and Busquet, Nicolas and Kovacs, Elizabeth J. and McCullough, Rebecca L.},
  year = {2024},
  month = Feb,
  pages = {303–316}
}